Moon Blindness in Horses Causes, Treatment, and Prevention By Katherine Blocksdorf Katherine Blocksdorf Kathy Blocksdorf is an equine expert and writer with over three decades of experience in training and riding horses. She was raised caring for horses, rehabilitated rescue horses, shows her own horses, and rides long distance. Learn more about The Spruce Pets' Editorial Process Updated on 12/10/25 Reviewed by Marla Fischl Equine Recurrent Uveitis, periodic ophthalmia or ERU can be mistaken for an eye infection. Credit: Image Credit:Jaclyn Sollars/ Moment /Getty Images Key Takeaways Moon blindness, or equine recurrent uveitis (ERU), is a progressive autoimmune condition and the leading cause of blindness in horses.Symptoms include eye pain, sensitivity to sunlight, and recurrent inflammation, which can lead to permanent blindness if untreated.Early veterinary intervention and ongoing management can slow disease progression, but there is no cure for moon blindness. Moon blindness, an inflammatory eye condition, was historically named for its misperceived association with the moon's phases. We now know that moon blindness has nothing to do with the moon but can recur over the course of weeks or months. It causes pain and discoloration of the eye, and affected horses are very sensitive to bright sunlight. Some horse breeds seem to be more susceptible than othersâappaloosas, in particular. Because this condition is progressive and can cause blindness, owners should seek veterinary help as soon as symptoms appear. What Is Moon Blindness? Technically known as equine recurrent uveitis (ERU), moon blindness is generally considered to be an autoimmune condition characterized by recurrent inflammatory episodes in one or both eyes. It is the most common cause of blindness in horses. Symptoms of Moon Blindness Symptoms of moon blindness involve one or both eyes. A horse will be reluctant to be in bright sunlight, exhibiting signs of pain or irritation that are not relieved by antibiotic treatment. Symptoms InflammationRedness of the eye areaMurkiness or white discoloration of the eyeTearing (watering)SquintingBlindness Some horses with moon blindness may suffer recurrent bouts of inflammation, followed by relatively painless periods. Others experience constant low-level inflammation. Owners may initially attribute redness, tearing, and squinting to an environmental irritant or eye infection, but measures to treat these conditions will have little effect on moon blindness. Moon blindness is regarded as recurrent because it appears to clear up and then spontaneously reoccurs. For some horses, the recurrence may occur over years or flare-ups may occur far more frequently, episodes happening within weeks or even days. Untreated, moon blindness can lead to cataract formation or prolonged inflammation, both of which are likely to lead to permanent blindness. Causes of Moon Blindness There are several possible causes for moon blindness, although a genetic predisposition to autoimmunity probably underlies external triggers, which may include: Bacteria (leptospirosis) Vitamin deficiencies Physical injuries Equine flu Tooth and hoof abscesses De-worming medication Appaloosas and German warmbloods are two breeds that seem particularly vulnerable to moon blindness due to hereditary factors. Diagnosing Moon Blindness in Horses To diagnose moon blindness, your veterinarian will consider the horse's recent ocular heath history. Recurrent episodes of inflammation are indicative of moon blindness and help rule out other eye problems. In addition, your veterinarian will perform extensive eye exams, including a fluorescein stain, to determine the health of the cornea and retina. How to Treat Moon Blindness in Horses Treatment options for moon blindness include steroids, non-steroidal anti-inflammatory drugs (NSAIDs), and mydriatics for inflammation and pain. During an acute flare of moon blindness, it's important to protect your horse from bright light with either a mask or by keeping it indoors. Each time this condition reoccurs, you will need to resume treatment. Frequent flares may prompt some horse owners to resort to euthanasia. If only one eye is affected, the eye can be removed. Surgery to implant a drug-laden disc in the eyes seems to hold some promise, but it is not yet common practice. Prognosis for Horses with Moon Blindness Unfortunately, there is no cure for moon blindness, but early treatment can help slow the progression of the disease. More than half of the horses that develop moon blindness will eventually become blind. How to Prevent Moon Blindness Little can be done to prevent moon blindness, but providing good nutrition, a clean environment, fly control, and watchful care will help your horse be as healthy as possible. If you notice eye inflammation or discharge, call your veterinarian so that treatment, if needed, can be started promptly. If you suspect your pet is sick, call your vet immediately. For health-related questions, always consult your veterinarian, as they have examined your pet, know the pet's health history, and can make the best recommendations for your pet. Explore more: Horses Horse Health & Wellness Horse Diseases & Conditions Sources The Spruce Pets uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Equine Recurrent Uveitis. UC Davis Veterinary Medicine Center for Equine Health.