The 14 Best Probiotics for Cats of 2026

Best Overall

Purina Pro Plan FortiFlora for Cats

$31 at Amazon $31 at Chewy View on PetSmart

Purina Pro Plan FortiFlora is designed for cats prone to diarrhea who can benefit from the extra gut support provided by a supplemental dose of probiotics. Each sachet contains a liver-flavored powder you can sprinkle on top of your cat’s food or mix with a liquid, like broth.

There is only one probiotic strain in this formula, but it’s one that naturally occurs inside a cat’s small intestine. Other ingredients listed aren’t probiotic-related, but they do help support your cat’s digestion, like the fibrous psyllium husk and taurine, which aid in overall digestive function.

That said, we wish the labeling and overall product information provided by Purina were more transparent. For example, Purina states that this probiotic contains a guaranteed number of live active cultures per serving, but the exact count is never listed.

Nevertheless, it remains the probiotic brand most often recommended by veterinarians for help with digestive issues. Keep in mind that this is specifically formulated for dealing with diarrhea, and it may not be as effective for other gut-related problems like gas or anxiety.

_{Delivery Method: Powder | Quantity: 30 sachets | NASC Seal: No}

Best Chews

VetriScience Laboratories Probiotic Everyday Gut Health Supplement for Cats Soft Chews

$10 at Amazon View on Chewy View on Vetriscience.com

These VetriScience Probiotics Everyday chews are an easy and affordable way to treat your cat for healthy gut maintenance. Fish-shaped and duck-flavored, these chewy probiotics are likely to be mistaken for a treat by your unsuspecting cat. We like that each chew has 120 million colony-forming units (CFU) and contains a prebiotic, and that, when used daily, they can help keep things moving smoothly, contribute to your cat’s overall immune system, and help gassy kitties.

However, since they only contain one probiotic strain, they’re best used for maintenance and not for acute issues. Keep in mind that these treats contain several gluten ingredients, which may actually cause stomach upset in some cats, especially if they’re not used to it in their regular food.

_{Delivery Method: Chews | Quantity: 45, 60, 120 count | NASC Seal: No}

Best Budget

Pet Naturals of Vermont Daily Probiotic for Cats

$8 at Amazon View on Chewy View on Pureformulas.com

Sometimes cats will turn their nose up when powders are added to their food. That’s where a daily treat will come in handy to help them get their daily dose of probiotics. Pet Naturals of Vermont Probiotic is a great daily treat.

Around $6 for a 30-day supply, the cost won’t have to be the reason your cat is missing out on the benefits of daily pro- and prebiotics. This chew contains 100 million CFU of a single strain of gut bacteria, the proprietary Ganeden BC30 Bacillus coagulans. This strain forms spores that are capable of surviving excessive stomach acids so that they can aid in active, healthy digestion in the intestinal tract.

These duck-flavored chews also contain prebiotic fiber and arabic gum, as well as healing aloe vera gel. A bonus is that they are said to improve bad breath. 

You can keep these shelf-stable treats on hand in a cool, dry place for any time your cat needs an extra digestive boost or doesn’t get a full dose using another method. Pet Naturals of Vermont is a woman-owned business, and the treats have the NASC seal, so you can feel good about your purchase.

_{Delivery Method: Chew | Quantity: 30 chews | NASC Seal: Yes}

Best for Constipation

PetUltimates Probiotics for Cats

$33 at Amazon $33 at Chewy View on Petultimates.com

Constipation can be caused by a number of conditions. If this is an issue for your cat, it's important to consult with your vet, and you might consider adding Pet Ultimates Probiotics for Cats to your pet's diet.

Each scoop of this no-nonsense supplement contains 5 billion CFU of 20 strains of live healthy gut bacteria plus a source of fiber—beta-glucan—and alpha-galactosidase, a digestive enzyme that breaks down natural sugars so that they are easier to digest. That’s it.

Manufactured in the U.S. in a Food and Drug Administration-registered Good Manufacturing Practices (GMP)-compliant facility, this supplement claims to reduce litter box odors and help your cat make firmer stools.

_{Delivery Method: Powder | Quantity: 44 grams | NASC Seal: Yes}

Best for IBD

Fera Pets Probiotics with Prebiotics

$30 at Amazon $30 at Chewy View on Petco

Inflammatory bowel disease (IBD) is a syndrome in cats, a label applied to a collection of symptoms. It can present in your cat as diarrhea or constipation and is most commonly diagnosed in middle-aged to older cats, usually 5 to 12 years of age. The 12 live, powerful strains of living good bacteria in Fera Pets Organic Probiotics with Prebiotics may help manage IBD.

With 5 billion CFU per scoop, your cat won’t notice when you stir this flavorless powder in with their food. Fera Pets' formula has been certified organic by the U.S. Department of Agriculture (USDA), including the plant-based ingredients gum arabic and inulin that provide the bulk of the prebiotic fiber that will help your cat stay regular. FOS also works as a prebiotic to feed good gut bacteria.

This recipe was custom-formulated by co-founding veterinarian Michelle Dulake and is manufactured in the U.S. in FDA-registered GMP-compliant facilities and carries the NASC seal. Store in a cool, dry place for the best shelf life.

_{Delivery Method: Powder | Quantity: 60 scoops | NASC Seal: Yes}

Best Calming

Purina Calming Care Veterinary Supplements

$34 at Amazon View on Chewy View on Proplanvetdirect.com

This liver-flavored probiotic supplement has been shown to reduce anxious behaviors such as pacing, spraying, and meowing. Even better, it encourages positive behaviors such as playing and socializing, and can help relieve sneezing in cats infected with the herpes virus.

This cat supplement contains a proprietary formula that relies heavily on BL999 (Bifidobacterium longum), which has been scientifically linked to the gut’s regulation of mood and behavior and helps dial down cortisol, a known stress hormone. But you’ll need to be patient: It can take up to six weeks of a daily dose before you start to see the effects. (By comparison, probiotics taken for gut health show results after just one day or up to four weeks of use.) In addition to helping with anxious behaviors, this supplement can help calm your cat and help it adjust to new environments or new people and pets in its existing environment.

_{Delivery Method: Powder | Quantity: 30 sachets | NASC Seal: No}

Best Deodorizer

Skout's Honor Skout's Honor Probiotic Deodorizer

$15

$15 at Amazon $15 at Chewy $15 at Chewy

Your cat's personal microbiome isn't just in their stomach—they (and we) also have a living ecosystem on the surface of our skin! Skout's Honor Probiotic Deodorizer includes topical probiotics that are meant to encourage a healthy microbiome, crowding out bacteria that cause bad smells, dryness, and itching. While recent studies into topical probiotics have promising results—providing potential treatments for acne and psoriasis in humans, for example—the research isn't advanced enough to say for sure if probiotics really are effective deodorants.

But even absent specific probiotic claims, Skout's Honor Deodorizer makes a good case for itself by providing a hydrating and smell-reducing topical spray that can be used as needed. It includes natural ingredients like avocado oil to keep skin protected.

In addition to its hypoallergenic unscented version, Skout's Honor Probiotic Deodorizer is available in four different scents: Sandalwood Vanilla, Honeysuckle, Lilac & Linen, and Lavender.

_{Delivery Method: Spray | Quantity: 8 ounces | NASC Seal: No}

Best for Kidney Disease

Healthy Kidney Inc. Kidney Restore

$37

$23 at Amazon

Kidney disease in cats can sneak up on pet parents. Cats are often quiet about their symptoms, so we may not realize they’re struggling until kidney problems have advanced. It is most common in older cats, especially those over 10 years old, and you should consult with your vet about the best course of treatment.

Healthy Kidney’s Kidney Restore was formulated by naturopath Robert Galarowicz. The recipe focuses on balancing five critical aspects of kidney health to reduce renal stress. The formula claims to balance phosphorus, potassium, and acid buildup and support the elimination of toxins.

One scoop contains 50 billion CFU of seven strains of good bacteria. Camu camu powder and FOS are included as prebiotics. The formula also contains sodium bicarbonate to neutralize acids, niacinamide (vitamin B3) to lower harmful phosphorus levels, and vitamin C as an antioxidant. 

Organic, GMO-free, and manufactured and tested in an FDA-registered, GMP-compliant facility in the United States, it’s easy for your pets to take mixed in with food. Some cat owners report that their cats wouldn’t eat it, but many others saw noticeable improvements in their cats within a couple of weeks or less.

_{Delivery Method: Powder | Quantity: 90 grams | NASC Seal: No}

Best Immune Support

Vital Planet Flora Cat Probiotic

$33 at Amazon $30 at Chewy View on Vitacost

This high-potency probiotic powder contains 10 different probiotic strains, giving your cat more diversity than other probiotics on the market. And, while most probiotics only have one prebiotic, Vital Planet Flora Probiotic Powder contains two. In turn, your cat’s gut is being served more bang for your buck, resulting in a more profound effect on your cat’s immunity support and gut health.

This powder is unflavored, so it’s great for fussy eaters. Add this to your cat's food by sprinkling it on top, or mix it with a liquid like broth for easier administration.

We like that there are 20 billion active cultures per serving, so you’ll get a month’s worth in one container. We wish the one-scoop-fits-all dosage were more precise, though, since some cats can get a little gassy with a full scoop.

_{Delivery Method: Powder | Quantity: 30 scoops | NASC Seal: Yes}

Best for Kittens

Nutramax Proviable-DC

$20 at Amazon $20 at Chewy

$23

$22 at Petco

Nutramax Proviable-DC Capsules contain seven different types of probiotic strains, providing your kitten with a high level of diversity for maximum effectiveness. They’ve also got two different prebiotics that help with the colonization and growth of the included probiotics in the gastrointestinal environment. These probiotics come in a powder-filled capsule, which we’ve found to be a plus when administering to a kitten.

The dosage instructions are the same regardless of the age or weight of your cat, and we like that you can twist apart the capsule and distribute its contents over several meals throughout the day—clutch in those cases where the kitten may not finish their food or is a fussy eater. This probiotic is greenlit for daily use, but at the price point, it makes more sense to use it as needed for gut repair or to firm up cases of diarrhea.

_{Delivery Method: Capsule | Quantity: 30, 80 count | NASC Seal: No}

Best Syringe

PetAg Bene-Bac Plus FOS & Probiotics Gel Supplement

$28 at Amazon $13 at Chewy View on Petco

Kittens are generally born without gut bacteria. They develop a healthy gut from the bacteria they receive while nursing and while exploring their environment. But kittens separated from their mother too early, those fed poor diets, and those experiencing trauma may struggle to establish a healthy gut community.

PetAg Bene-Bac Plus Gel Digestive Supplement is an excellent solution because this combination of pro- and prebiotics comes in a syringe for easy measuring and dispensing. Each dose can be given by weight, with each gram containing 20 million CFU of seven strains of live healthy gut bacteria. PetAg also recommends this probiotic gel for traveling, post-birth, after worming, at weaning, while boarding, post-surgery, when dietary changes occur, post-antibiotic therapy, and as indicated by your pet's veterinarian.

Kittens will love the sweet flavor of the FOS prebiotic and sunflower oil in each dose. The syringe helps with precise measurement and can be stored at room temperature.

_{Delivery Method: Gel in syringe | Quantity: Three 15-gram syringes | NASC Seal: No}

Best Cat Food

Purina Pro Plan Complete Essentials Dry Food

$54 at Amazon $54 at Chewy View on Petco

If you'd like to skip the step of adding a probiotic supplement to your cat's diet, you can choose a food with probiotics included. Purina Pro Plan Complete Essentials is a nutritionally sound dry cat food, with real chicken or salmon first on the ingredient list.

The high-protein formula is designed for adult cats and features a blend of live probiotics (600 million CFU/pound of Bacillus coagulans) and prebiotics (from fiber) to support digestion and a healthy immune system. The food also provides omega-6 fatty acids for a healthy coat and skin. Additional ingredients include brewer's rice, eggs, animal fat, amino acids, and essential vitamins and minerals.

^{Delivery Method: Dry food | Quantity: 3.5, 7, 16 pounds | NASC Seal: No}

Best Food Topper

Zesty Paws Probiotic Powder for Cats

$28 at Amazon $28 at Chewy

$30

$28 at Petco

Some pet parents find it easier to incorporate cat supplements into their feline's food. This pumpkin-flavored probiotic powder from Zesty Paws offers the convenience of pre-dosed sachets—ideal for traveling—with over 400 million CFU per serving. It contains inulin, yeast extract, and DE111, a clinically studied Bacillus subtilis probiotic that supports gut health and immune system function for cats.

While the powder is designed to be sprinkled onto dry or wet food, it doesn't adhere quite as well to dry food, according to some users. The pumpkin flavor is generally liked by most cats, though it may not have the same appeal to finicky felines.

_{Delivery Method: Powder | Quantity: 30 sachets | NASC Seal: No}

Best Tasting Treat

Pet Honesty Daily Probiotics

$16 at Amazon $16 at Chewy

$20

$16 at Petco

Probiotic cat treats can only be as effective as they are appealing to your feline's palate. This daily supplement from Pet Honesty features a crunchy outer shell and a creamy core, offering an enticing combination of tastes and textures. It contains 500 million CFU of Bacillus subtilis (per 3 grams), along with prebiotics to promote gut health and fish oil for healthier skin and coat.

We also appreciate that this probiotic treat has the NASC seal of approval and is made without fillers, including corn, soy, and wheat. On the downside, the package is small, making it more expensive than some other options. Also, some pet parents report the treats having adverse effects on their kitties with sensitive stomachs.

_{Delivery Method: Chew | Quantity: 3.7 ounces | NASC Seal: Yes}