We independently evaluate all of our recommendations. If you click on links we provide, we may receive compensation. The 5 Best Milk Replacers for Kittens to Promote Healthy Growth Nutritious and safe options await By Katherine Alex Beaven Katherine Alex Beaven K. Alex Beaven is a writer for The Spruce Pets. Learn more about The Spruce Pets' Editorial Process Updated on 03/21/25 In This Article View All In This Article Top Picks Reviews What to Know FAQ Why Trust The Spruce Pets Credit: The Spruce Pets / Amelia Manley Milk replacement for kittens should always be a secondary option as kittens have a better chance of surviving and thriving when they nurse from their mother or another lactating cat, especially during the first two days of life. Mother’s milk contains important bacteria that help to set the foundation of their gastrointestinal system and immune function. However, countless animal rescues know this isn’t always possible so finding a reliable kitten milk replacer, also called kitten formula, is paramount for anyone bottle-feeding a kitten. Choosing the right kitten formula will ensure your young kitten gets the vital nutrients and calories it needs to grow into a healthy, full-sized cat. Because of its high-calorie and high-protein content, kitten milk replacer is also often used to nourish pregnant cats, lactating cats, and sick or underweight cats. At the top of our list is the popular PetAg KMR Powder, but it may not be the right kitten formula for you and your kitten, so we found several other powder formulas since they are generally accepted as superior to liquid options. Top Picks Best Overall: PetAg KMR Kitten Milk Replacer at Amazon $32 Jump to Review Best Powder: Nutri-Vet Milk Replacer with Opti-Gut for Kittens at Amazon $28 Jump to Review Best for Weaning: PetAg KMR 2nd Step Kitten Weaning Formula Powder at Amazon $20 Jump to Review Best Value: Hartz Powdered Kitten Milk Replacer at Amazon $13 Jump to Review Recommended on Reddit: Breeder's Edge Kitten Milk Replacer at Amazon $36 Jump to Review Best Overall PetAg KMR Kitten Milk Replacer Credit: Amazon $32 at Amazon $12 at Chewy $14 $12 at Petco What We Like Contains prebiotics and probiotics Able to refrigerate leftover mixed portions Shelf-stable powder formula Also works as a calorie supplement in adult cats AAFCO approved What We Don’t Like Can be lumpy PetAg KMR Powder is considered the gold standard for kitten formula—one of the few approved by the Association of American Feed Control Officials (AAFCO)—and young cats on this kitten milk replacement can thrive. Made from cow’s milk, it is designed to mimic cat’s milk as closely as possible, providing developing newborn kittens and kittens up to six weeks old with the vital nutrients and calories for healthy growth. It also contains prebiotics and probiotics to support a healthy gut and can even double as a calorie and nutritional supplement for sick, malnourished, or lactating adult or senior cats. Preparation only requires a bit of hot water, though it can be frustrating when the powder doesn’t dissolve and the clumps clog the bottle nipple. Unused portions can be refrigerated for up to 24 hours—just be sure to rewarm before serving. Compared to the liquid version, which must be refrigerated after opening and used entirely within 72 hours, this powder formula will stay shelf-stable for up to a year and last for two months on the shelf after opening, or three months in the refrigerator and up to six months in the freezer. Primary Ingredients: Casein, vegetable oil, dried skim milk | Volume: 12 ounces Best Powder Nutri-Vet Milk Replacer with Opti-Gut for Kittens Credit: Amazon $28 $24 at Amazon $25 at Chewy $29 $25 at Walmart What We Like Mixes smoothly into warm water Made in the United States Lasts three months in the fridge and six in the freezer, opened Contains Opti-Gut probiotics Vet formulated What We Don’t Like Some cats don’t like the taste A solid powdered kitten milk product with a good track record when it comes to quality and effectiveness, this Nutri-Vet Milk Replacer stands out among other powdered kitten milk replacements because it typically dissolves more smoothly into warm water. Less clumping means you’ll have less hassle during preparation and feeding, which can be a gift when taking care of adorable but needy kittens up to six weeks old. It’s also less expensive than our best overall pick, which may be a deciding factor for budgeting pet parents. The vet-formulated recipe contains all the essential vitamins, amino acids, and minerals tiny and growing kittens need to properly develop, along with a proprietary Opti-Gut probiotic formula to support gastrointestinal health, which can set them up with an immune advantage. It can also be used as a nutritional supplement for pregnant, nursing, or underweight cats. Fair warning: the flavor is not always a winner with the kitties—especially if they’ve started with a different type of formula—so transitioning can be rough and adult cats may need it to be mixed with their usual food. Primary Ingredients: Animal fat, vegetable fat, dried whey | Volume: 12 ounces Best for Weaning PetAg KMR 2nd Step Kitten Weaning Formula Powder Credit: Petco $20 at Amazon $25 $20 at Petco View on Tractor Supply Co. What We Like Served in a bowl Easy 3:1 preparation Fulfills basic nutrition needs while transitioning What We Don’t Like May cause stomach upset and diarrhea This PetAg kitten milk replacer is specifically formulated to help your 6-to-8-week-old kitten graduate from formula to solid food. Unlike the traditional formula, which contains casein and vegetable fats for caloric density, the first ingredient in this weaning formula is rice flour. This is because you’ll be supplementing calories with solid wet or dry food. Like the traditional PetAg KMR, it’s made with cow’s milk (there is no goat’s milk alternative for this one). An easy 3:1 preparation recipe creates a broth-like formula that—thankfully—should be served in a bowl. Whereas first-step kitten milk replacer can sometimes cause constipation, this weaning formula may cause diarrhea as your cat’s gut adjusts. Primary Ingredients: Rice flour, dried meat, dried milk | Volume: 14 ounces Best Value Hartz Powdered Kitten Milk Replacer Credit: Amazon $13 $13 at Amazon View on Chewy What We Like Easy to mix Fattens up skinny kittens quickly Dissolves smoothly Can also be used to wean What We Don’t Like Cannot be frozen to extend life Raising a newborn kitten, or any kitten for that matter, is expensive. Between vet visits, kitten-proofing your home, buying the necessary new-cat accessories, and attending to their voracious appetite, opting for a solid value kitten milk replacer can help buoy your budget. This Hartz Powdered Kitten Milk Replacer is accepted by most kittens and also works to add weight to underweight adult cats. We like that, at a different mixing ratio, it can be used for weaning, though this may increase the risk of constipation and works best if you’ve been using it as your regular formula. The powder tends to dissolve well in warm water, especially if using a whisk or frother. The unused formula can be stored in the fridge for up to 24 hours, and once opened the entire container should be refrigerated and used within two months—however, it cannot be stored in the freezer like the PetAg KMR. Primary Ingredients: Animal fat, vegetable fat, dried whey protein | Volume: 11 ounces Recommended on Reddit Breeder's Edge Kitten Milk Replacer Credit: Amazon $36 at Amazon What We Like Blends easily with no clumps Longer shelf life than some other brands Doesn't need to be refrigerated Includes probiotic for digestive health Less chance of diarrhea What We Don't Like May not work for kittens prone to constipation Across different forums on Reddit, such as FosterAnimals and catcare, Breeder's Edge is a popular choice amongst users, with some even favoring it over our top pick PetAg KMR. Several commenters think Breeder's Edge is on par with PetAg KMR in terms of high-quality nutrition but better for kittens with sensitive tummies and less likely to cause diarrhea. Other users note rescue shelters' preference for Breeder's Edge because "it has a longer shelf life and doesn't need to be refrigerated." Not having to be refrigerated also means fewer clumps, making Breeder's Edge Foster Care Kitten Milk Replacer easier to blend—just dissolve the powder in warm water. Plus, fans of the formula like that it contains probiotics for digestive health and whey protein to promote steady weight gain, which is vital for malnourished, at-risk rescue kittens. However, it should be noted that while this kitten milk replacement powder is great for preventing diarrhea, it may not be the best choice for kittens prone to constipation and can, in some cases, cause more blockage. Primary Ingredients: Dried whey protein concentrate, animal fat, vegetable oil | Volume: 12 ounces Final Verdict Our overall pick for the best kitten milk replacer is a foster and rescue favorite, the PetAg KMR Powder. If it’s in your budget, the quality is top notch and we like that it can be stored in the freezer to extend the use-by date to a total of six months. That said, the Hartz Powdered Kitten Milk Replacer is nothing to sneeze at since it still offers solid ingredients and results at a much lower price point. It’s a great budget pick. What to Know About Kitten Milk Replacer How to Bottle Feed Select a nipple shape that appeals most to your kitten. Suckling is a natural instinct, but newborns may need a little guidance and have nipple preferences. Prepare the formula and warm it to approximately 100 degrees Fahrenheit. Test it on your hand to make sure it’s not too hot. Place your kitten in the feeding area, keeping its belly down. Positioning matters, so do not pick the kitten up or cradle it on its back. Gently hold the kitten in place with your non-dominant hand. Guide the nipple into your kitten’s mouth until it latches on, and then raise it at a slight angle that allows for the easy and steady flow of formula with minimal suckling effort. Too low and the kitten may have to work too hard and become discouraged; too high and they could choke or ingest too much air. After the kitten finishes their allotted serving, record the kitten's weight so you can track their progress and adjust the volume of formula needed for each feed as they grow. Feeding Schedule Baby animals, including humans, require around-the-clock feeding. Plan on bottle-feeding a kitten every two to four hours. Growing kittens burn through their calories at a lightning pace as their little bodies work overtime to continue to develop organs and systems, and create new cells and tissues at a rapid rate. As kittens grow larger, they will require less frequent feedings. If your kitty seems to be growing too large or not large enough, ask your vet for advice on how to adjust your feeding schedule and/or portion size. Nutrition As mentioned, kitten bodies are hard at work and require significantly more calories at mealtime than adult cats. Even after weaning your kitten, the food you give them should be formulated for kittens and fed to them for up to a year. Kittens require about 30 percent of their calories from protein, benefit from the extra calories of fats, and need different amounts of minerals, amino acids, and vitamins than adult cats. Izzy Nidetz, director of placement for the Pasadena Humane Society, also suggests looking for kitten formula containing the following: Probiotics and Fiber: Help to support the gut and prevent or lessen constipation (which Nidetz says is extremely common for kittens on formula).Taurine: An essential amino acid that all cats, regardless of age, need to live. Calcium: For strong and healthy bone development. Weaning Most kittens start the weaning process by around week six, usually around the four or five-week mark, with indications of tooth development. “Their canines should be fully erupting,” says Nidetz, “and premolars should be emerging when they are ready to start transitioning to more solid food.” Ultimately, the weaning process will be decided by your kitten, but Nidetz cautions to take it slow, with patience. Make a gradual transition from kitten formula to solid foods, slowly increasing the ratio of solid foods. At the Pasadena Humane Society, Nidetz says they usually will mix KMR with kitten-formulated wet food to make what they’ve dubbed a “slurry” to help the kitten’s digestive tract start accepting the new type of food. “Once they get the hang of the slurry, you can transition them to wet food fully.” FAQ Can you make homemade kitten milk replacer? There is no one recipe for making homemade kitten milk replacer, but they usually contain a source of protein, fat, and sugar. It’s common to see easy-to-source ingredients like some type of milk, egg yolks, vegetable oil, and a sugar syrup. But while it is possible to make homemade kitten milk replacer, it can be time-consuming and it’s widely understood that manufactured kitten formula is better for kittens since it has all the essential amino acids, vitamins, minerals, and balance of caloric content that is vital to a kitten’s development.The first six weeks of a kitten’s life are when the building blocks of their bodies, like gut and immune system, are developed and any deficit in necessary nutrients can have lifelong effects on your kitten’s health. This is definitely a time when it’s better to seek veterinary guidance and let the pros lead the way. Does kitten milk replacer need to be refrigerated? In short, yes. Whether you are mixing up a powdered formula or warming up a liquid product, you’ll need to refrigerate any unused portion. The refrigerated portion should be used within 24 hours or else discarded. After opening, a liquid formula should be refrigerated in its container and stored only as long as the manufacturer specifies (usually around a week or two). We also recommend storing all opened powdered formulas for optimal longevity.Check the manufacturer’s guidance on how long it will stay fresh for use (usually around two to three months). Some powdered formulas can be stored in the freezer for extra longevity, but not all. Always read labels or contact manufacturers with specific questions to keep your pet safe. Why Trust The Spruce Pets K. Alex Beaven is a lifelong cat owner who once woke up to a fresh litter of kittens meowing under her bed. As a child, she was known to rescue strays on the regular, promising to find them (other) homes, but they almost all were foster fails. For this story, Alex gained insight from Izzy Nidetz, Director of Placement for Pasadena Humane Society, on what to look for in a good kitten milk replacer and tips on how to bottle feed small cats. Alex has also written stories for The Spruce Pets on The Best Kitten Foods, Best Bone Broth for Cats, and Best Lickable Cat Treats. Explore more: What to Buy Cat Products Cat Food